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cognitive psychology, drug trials, cognitive testing, neuropsychology, cognitive research, computer-automated cognitive tests, computerised test battery, cognitive tests, CANTAB, CANTAB tests, CANTAB test battery, MCI, mild cognitive impairment, early detection of AD, Early detection of Alzheimer's Disease, clinical screening, screening for AD, screening for Alzheimer's Disease, dementia, Alzheimer's Disease, cognitive norms, Graded Naming Test, Expedio, CANTABexpedio, PAL on PDA, Reaction time, Memory clinic, Clinical trials, Memory loss, 21CFRpart11, neuroscience, neuropsychological assessment
 
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cognitive psychology, drug trials, cognitive testing, neuropsychology, cognitive research, computer-automated cognitive tests, computerised test battery, cognitive tests, CANTAB, CANTAB tests, CANTAB test battery, MCI, mild cognitive impairment, early detection of AD, Early detection of Alzheimer's Disease, clinical screening, screening for AD, screening for Alzheimer's Disease, dementia, Alzheimer's Disease, cognitive norms, Graded Naming Test, Expedio, CANTABexpedio, PAL on PDA, Reaction time, Memory clinic, Clinical trials, Memory loss, 21CFRpart11, neuroscience, neuropsychological assessment
cognitive psychology, drug trials, cognitive testing, neuropsychology, cognitive research, computer-automated cognitive tests, computerised test battery, cognitive tests, CANTAB, CANTAB tests, CANTAB test battery, MCI, mild cognitive impairment, early detection of AD, Early detection of Alzheimer's Disease, clinical screening, screening for AD, screening for Alzheimer's Disease, dementia, Alzheimer's Disease, cognitive norms, Graded Naming Test, Expedio, CANTABexpedio, PAL on PDA, Reaction time, Memory clinic, Clinical trials, Memory loss, 21CFRpart11, neuroscience, neuropsychological assessment
CANTAB - Attention tests
cognitive psychology, drug trials, cognitive testing, neuropsychology, cognitive research, computer-automated cognitive tests, computerised test battery, cognitive tests, CANTAB, CANTAB tests, CANTAB test battery, MCI, mild cognitive impairment, early detection of AD, Early detection of Alzheimer's Disease, clinical screening, screening for AD, screening for Alzheimer's Disease, dementia, Alzheimer's Disease, cognitive norms, Graded Naming Test, Expedio, CANTABexpedio, PAL on PDA, Reaction time, Memory clinic, Clinical trials, Memory loss, 21CFRpart11, neuroscience, neuropsychological assessment
 
These tests measure different aspects of attention and reaction time. Choice Reaction Time (CRT) , Rapid Visual Information Processing (RVP) and Simple Reaction Time (SRT) use the press pad exclusively as an input device; Match to Sample Visual Search (MTS) and Reaction Time (RTI) use both the press pad and the touch screen.

 

Choice Reaction Time (CRT)


Overview
Choice Reaction Time (CRT) is a 2-choice reaction time test which is similar to the Simple Reaction Time (SRT) test, except that stimulus and response uncertainty are introduced by having two possible stimuli and two possible responses. It is useful for testing general alertness and motor speed.

Administration time
Around 7 minutes, depending on level of impairment.

Task
An arrow-shaped stimulus is displayed on either the left or the right side of the screen.
The subject must press the left hand button on the press pad if the stimulus is displayed on the left hand side of the screen, and the right hand button on the press pad if the stimulus is displayed on the right hand side of the screen.

Test modes
Clinical mode.

Outcome measures
This test has thirteen outcome measures, assessing correct and incorrect responses, errors of commission and omission (late and early responses), and latency (response speed).
 

Match to Sample Visual Search (MTS)


Overview
Match to Sample Visual Search (MTS) is a matching test, with a speed/accuracy trade-off. It is a simultaneous visual search task with response latency dissociated from movement time. Efficient performance on this task requires the ability to search among the targets and ignore the distractor patterns which have elements in common with the target. This test can help to differentiate between Parkinson's disease and Alzheimer's disease, and also between Lewy Body dementia and Alzheimer's disease.

Administration time
Around 9 minutes, depending on level of impairment

Task
The subject is shown a complex visual pattern (the sample) in the middle of the screen, and then, after a brief delay, a varying number of similar patterns is shown in a circle of boxes around the edge of the screen. Only one of these boxes matches the pattern in the centre of the screen, and the subject must indicate which it is by touching it. Reaction time is measured on the basis of the release of the press-pad, which allows for its more accurate measurement.

Test modes
Clinical mode

Outcome measures
The twelve outcome measures for SOC cover the number of problems solved with minimum moves, the mean number of moves for n-move problems, mean initial thinking time for n-move problems and mean subsequent thinking time for n-move problems.
 

Reaction Time (RTI)


Overview
Reaction Time (RTI) is a latency task with a comparative history (the five choice task) and uses a procedure to separate response latency from movement time. It is more useful than CRT or SRT where it is necessary to control for tremor.
Click for an interactive demonstration
click for an interactive demonstration

Administration time
Around 5 minutes, depending on level of impairment.

Task
The task is divided into five stages, which require increasingly complex chains of responses. In each case, the subject must react as soon as a yellow dot appears. In some stages the dot may appear in one of five locations, and the subject must sometimes respond by using the press-pad, sometimes by touching the screen, and sometimes both.

Test modes
Clinical mode, parallel mode and child mode

Outcome measures
The four outcome measures in RTI are divided into reaction time (simple and 5-choice) and movement time (simple and five-choice).
 

Rapid Visual Information Processing (RVP)


Overview
Rapid Visual Information Processing (RVP) is a test of sustained attention (similar to the Continuous Performance Task) and has proved useful in many studies in which drugs are used to help develop a disease model.. It is sensitive to dysfunction in the parietal and frontal lobe areas of the brain and is also a sensitive measure of general performance.

Administration time
Around seven minutes.

Task
A white box appears in the centre of the computer screen, inside which digits, from 2 to 9, appear in a pseudo-random order, at the rate of 100 digits per minute. Subjects are requested to detect target sequences of digits (for example, 2-4-6, 3-5-7, 4-6-8) and to register responses using the press pad.

Test modes
Clinical mode, plus 123 mode (for children aged 4-8) and 357 mode (for children aged 7-14).

Outcome measures
The nine RVP outcome measures cover latency, probabilities and sensitivity (calculated using Signal Detection Theory), and hits, misses, false alarms and rejections.
 

Simple Reaction Time (SRT)


Overview
Sjmple Reaction Time (SRT) is a test which measures simple reaction time through delivery of a known stimulus to a known location to elicit a known response. The only uncertainty is with regard to when the stimulus will occur, by having a variable interval between the trial response and the onset of the stimulus for the next trial. Like Choice Reaction Time (CRT) it is useful for testing general alertness and motor speed, and is often sensitive to medication effects.

Administration time
Around 6 minutes, depending on level of impairment.

Task
As soon as the subject sees the square on the screen, they must press the button on the press pad.

Test modes
Clinical mode

Outcome measures
The eleven outcome measures for SRT cover latency (response speed), correct responses and errors of commission and omission.

 

cognitive psychology, drug trials, cognitive testing, neuropsychology, cognitive research, computer-automated cognitive tests, computerised test battery, cognitive tests, CANTAB, CANTAB tests, CANTAB test battery, MCI, mild cognitive impairment, early detection of AD, Early detection of Alzheimer's Disease, clinical screening, screening for AD, screening for Alzheimer's Disease, dementia, Alzheimer's Disease, cognitive norms, Graded Naming Test, Expedio, CANTABexpedio, PAL on PDA, Reaction time, Memory clinic, Clinical trials, Memory loss, 21CFRpart11, neuroscience, neuropsychological assessment
 
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